Omics

Within the EnvironMENTAL project, the STRATIFY cohort was enriched with newly generated multi-omics data, enabling cross-cohort comparisons and mechanistic analyses.

 

DNA Genotyping
Acquisition centre: Life & Brain (L&B)
Genome-wide genetic profiling to assess inherited susceptibility and support risk prediction analyses.

 

DNA Methylation
Acquisition centre: Life & Brain (L&B)
Epigenetic profiling to detect biological signatures associated with environmental exposure.

RNA Sequencing
Acquisition & analysis centre: Universitätsklinikum Bonn (UKB)
Gene expression profiling to investigate molecular responses to genetic and environmental factors.

Proteomics
Acquisition centre: Charité, Universitätsmedizin Berlin
High-throughput protein profiling to identify circulating biomarkers and pathway alterations.